HBA-USA members that conduct research on "Molecular Genetics"
- Ageing
John Papaconstantinou
University of Texas, School of Medicine, Professor
Molecular Genetics of Aging and Longevity
jpapacon@utmb.edu
- Cardiovascular Disease
Maria Irene Kontaridis
Harvard/Beth Israel Deaconess Medical Center, Assistant Professor of Medicine
Understanding the signaling pathways that mediate cardiac developmental processes may reveal important clues into the cellular and molecular pathogenesis of heart
disease. Specifically, we want to understand how protein-tyrosine phosphatases (PTPs) relate to cardiac development and disease. Our lab's research efforts focus on
developmental biology, in vivo analysis of in mouse systems, including disease models, and cardiac biology and stem cell research using primary cultures. Currently,
we are studying mouse models in which we can assess the molecular pathogenesis of the cardiac defects associated with Noonan (NS) and LEOPARD (LS)
Syndromes, pediatric disorders both attributed primarily to mutations in Shp2, the SH2 domain-containing protein tyrosine phosphatase
mkontari@bidmc.harvard.edu
- Cancer
Demetrios Kalaitzides
Beth Israel Medical Center/Harvard Medical School, Post-doctoral fellow
My current research interest include identifying novel cellular and molecular targets in Ras/MAPK-driven malignancies. Approaches include genome-wide RNAi
screens to identify synthetic-lethal interactions with oncogenic RAS and mouse leukemia models (oncogenic Ras/Shp2) to identify/characterize leukemia initiating cells
dkalaitz@bidmc.harvard.edu
Angela Papageorgiou
Massachussetts General Hospital, Research Fellow
Cancer, Endocrinology, Signaling Pathways
angelapapage@yahoo.com
Thales Papagiannakopoulos
University of California, Santa Barbara, PhD candidate
With over 600 miRNA genes identified experimentally in the human genome and a plethora of computatiaonally predicted mRNA targets, it is believed that these small
RNAs have a central role in diverse cellular and developmental processes. Therefore aberrant expression of miRNA genes could lead to human disease, including
cancer. Studies from our group and other have confirmed that miRNAs regulate cell proliferation and apoptosis. Furthermore, these non-coding RNAs can control
cellular identity and mediate differentiation.
miRNAs are playing an important role in inducing and maintaining the oncogenic state of various types of cancer. This function lies within their ability to target multiple
transcripts including many tumor suppressor genes or oncogenes.
With the use of gliomas as a model, I aim to determine the role of miRNAs in epigenetically regulating oncogenesis and tumor maintenance.
papagian@lifesci.ucsb.edu
Athanasios Papakostas
Massachusetts Eye & Ear Infirmary/ Harvard Medical School
THE ROLE OF MULLERIAN INHIBITING SUBSTANCE IN THE TREATMENT OF OCULAR MELANOMA-SNP ARRAY IN OCULAR MELANOMA
thanos_papakostas@meei.harvard.edu
Christos Tzimas
University of Pennsylvania, Post doctoral fellow
Cancer stem cells
chtzimas@gmail.com
Athanassios Vassilopoulos
NIDDK/NIH, Visiting Postdoctoral Fellow
Cell cycle, cancer stem cells
vassiloa@niddk.nih.gov
- Development
Konstantinos Zarbalis
UC Davis, Dept. of Pathology/Shriners Hospitals, Assistant Professor
My research is focused on the development of the forebrain and craniofacial structures. Using the mouse as a model organism we analyze mechanisms and the
molecular control involved in developing the forebrain and face.
kzarbalis@ucdavis.edu
- Evolution
Dimitra Chalkia
University of California, Irvine, Post-doctoral scholar
Role of naturally occurring human mitochondrial DNA variation in human health and disease; theoretical studies on the evolution of mitochondrial genes
dchalkia@uci.edu
Nikolas Nikolaidis
California State University, Fullerton, Assistant Professor
nnikolaidis@fullerton.edu
- Immunology
Nikolaos Patsopoulos MD, PhD
Brigham & Women's Hospital, Harvard Medical School, Research Fellow
Statistical Genetics
npatsopoulos@rics.bwh.harvard.edu
- Hearing disorders
Argyro J. Bizaki
Harvard Medical School, Department of Otolaryngology M.E.E.I
Molecular Biology in Otosclerosis-Hearing Disorders
argyro_bizaki@meei.harvard.edu
Nikoletta Charizopoulou
NIH/NIDCD, Postdoctoral visiting Fellow
Hearing Reseach, Neuroscience, Molecular Genetics, Animal Science
ncharizopoulou@yahoo.com
- Lung Disease
Joanna Floros, PhD
Pennsylvania State University College of Medicine, Evan Pugh Professor of Pediatrics and Obstetrics & Gynecology, Director of The Penn State Center for Host
defense, Inflammation and Lung Disease (CHILD) Research
Study of the molecular basis of individual variability to disease susceptibility with special emphasis on molecules and mechanisms involved in host defense and
inflammation. Genome wide SNP analysis of several hundred candidate genes will be performed using the Illumina Infinium Platform
jfloros@psu.edu
- Metabolic Diseases
Gerasimos Sykiotis
Massachusetts General Hospital & Harvard Medical School, Clinical & Research Fellow in Reproductive Endocrinology
I have broad interests in the genetics of endocrine diseases, and especially in metabolism and reproduction. I am particularly interested in the role of cellular stress
response pathways in the homeostasis of the endocrine system
gsykiotis@partners.org
- Microbiology
Georgia Mitsi, PhD, MBA, MSc
United Biosource, Manager
Molecular Genetics, microbiology
yiolamitsi@yahoo.gr
- Nephrology
Pinelopi Kapitsinou
Vanderbilt University, Clinical Fellow
Contribution of hypoxia inducible factors (HIFs) in chronic kidney disease progression,and hypoxic regulation of erythropiesis
Pinelopi.kapitsinou@vanderbilt.edu
-Nervous system development
Nikolaos Giagtzoglou
Baylor College of Medicine, Post-doctoral fellow
Developmental Biology
giagtzog@bcm.tmc.edu
- Neurodegeneration
Evangelia Sotiriou
Columbia University, MD, Post-doctoral researcher
Mitochondrial Diseases
es2802@columbia.edu
Sotiria Sotiriou
UCSF-JHU-NIH, PhD candidate
Neurodegeneration, Post-transcriptional regulation
ria_sotiriou@hotmail.com
- Neuroscience
Dimitrios Arkilo, MD
Tufts, Floating Hospital for Children, Fellow, Pediatric Neurology
Hypothermia in neuroprotection. Neuronal migration defects
arkdimi@hotmail.com
Nikolaos Patsopoulos MD, PhD
Brigham & Women's Hospital, Harvard Medical School, Research Fellow
Statistical Genetics
npatsopoulos@rics.bwh.harvard.edu
- Pulmonary DIseases
Eleni Vergadi
Children's Hospital Boston, Research Fellow in Pediatrics
Pulmonary Diseases, Molecular Genetics , Immunology
eleni.vergadi@childrens.harvard.ed
- Other
Marianna Feretzaki
Duke University, Graduate student
Genetics of Cryptococcus neoformasn
mf55@duke.edu
- Ageing
John Papaconstantinou
University of Texas, School of Medicine, Professor
Molecular Genetics of Aging and Longevity
jpapacon@utmb.edu
- Cardiovascular Disease
Maria Irene Kontaridis
Harvard/Beth Israel Deaconess Medical Center, Assistant Professor of Medicine
Understanding the signaling pathways that mediate cardiac developmental processes may reveal important clues into the cellular and molecular pathogenesis of heart
disease. Specifically, we want to understand how protein-tyrosine phosphatases (PTPs) relate to cardiac development and disease. Our lab's research efforts focus on
developmental biology, in vivo analysis of in mouse systems, including disease models, and cardiac biology and stem cell research using primary cultures. Currently,
we are studying mouse models in which we can assess the molecular pathogenesis of the cardiac defects associated with Noonan (NS) and LEOPARD (LS)
Syndromes, pediatric disorders both attributed primarily to mutations in Shp2, the SH2 domain-containing protein tyrosine phosphatase
mkontari@bidmc.harvard.edu
- Cancer
Demetrios Kalaitzides
Beth Israel Medical Center/Harvard Medical School, Post-doctoral fellow
My current research interest include identifying novel cellular and molecular targets in Ras/MAPK-driven malignancies. Approaches include genome-wide RNAi
screens to identify synthetic-lethal interactions with oncogenic RAS and mouse leukemia models (oncogenic Ras/Shp2) to identify/characterize leukemia initiating cells
dkalaitz@bidmc.harvard.edu
Angela Papageorgiou
Massachussetts General Hospital, Research Fellow
Cancer, Endocrinology, Signaling Pathways
angelapapage@yahoo.com
Thales Papagiannakopoulos
University of California, Santa Barbara, PhD candidate
With over 600 miRNA genes identified experimentally in the human genome and a plethora of computatiaonally predicted mRNA targets, it is believed that these small
RNAs have a central role in diverse cellular and developmental processes. Therefore aberrant expression of miRNA genes could lead to human disease, including
cancer. Studies from our group and other have confirmed that miRNAs regulate cell proliferation and apoptosis. Furthermore, these non-coding RNAs can control
cellular identity and mediate differentiation.
miRNAs are playing an important role in inducing and maintaining the oncogenic state of various types of cancer. This function lies within their ability to target multiple
transcripts including many tumor suppressor genes or oncogenes.
With the use of gliomas as a model, I aim to determine the role of miRNAs in epigenetically regulating oncogenesis and tumor maintenance.
papagian@lifesci.ucsb.edu
Athanasios Papakostas
Massachusetts Eye & Ear Infirmary/ Harvard Medical School
THE ROLE OF MULLERIAN INHIBITING SUBSTANCE IN THE TREATMENT OF OCULAR MELANOMA-SNP ARRAY IN OCULAR MELANOMA
thanos_papakostas@meei.harvard.edu
Christos Tzimas
University of Pennsylvania, Post doctoral fellow
Cancer stem cells
chtzimas@gmail.com
Athanassios Vassilopoulos
NIDDK/NIH, Visiting Postdoctoral Fellow
Cell cycle, cancer stem cells
vassiloa@niddk.nih.gov
- Development
Konstantinos Zarbalis
UC Davis, Dept. of Pathology/Shriners Hospitals, Assistant Professor
My research is focused on the development of the forebrain and craniofacial structures. Using the mouse as a model organism we analyze mechanisms and the
molecular control involved in developing the forebrain and face.
kzarbalis@ucdavis.edu
- Evolution
Dimitra Chalkia
University of California, Irvine, Post-doctoral scholar
Role of naturally occurring human mitochondrial DNA variation in human health and disease; theoretical studies on the evolution of mitochondrial genes
dchalkia@uci.edu
Nikolas Nikolaidis
California State University, Fullerton, Assistant Professor
nnikolaidis@fullerton.edu
- Immunology
Nikolaos Patsopoulos MD, PhD
Brigham & Women's Hospital, Harvard Medical School, Research Fellow
Statistical Genetics
npatsopoulos@rics.bwh.harvard.edu
- Hearing disorders
Argyro J. Bizaki
Harvard Medical School, Department of Otolaryngology M.E.E.I
Molecular Biology in Otosclerosis-Hearing Disorders
argyro_bizaki@meei.harvard.edu
Nikoletta Charizopoulou
NIH/NIDCD, Postdoctoral visiting Fellow
Hearing Reseach, Neuroscience, Molecular Genetics, Animal Science
ncharizopoulou@yahoo.com
- Lung Disease
Joanna Floros, PhD
Pennsylvania State University College of Medicine, Evan Pugh Professor of Pediatrics and Obstetrics & Gynecology, Director of The Penn State Center for Host
defense, Inflammation and Lung Disease (CHILD) Research
Study of the molecular basis of individual variability to disease susceptibility with special emphasis on molecules and mechanisms involved in host defense and
inflammation. Genome wide SNP analysis of several hundred candidate genes will be performed using the Illumina Infinium Platform
jfloros@psu.edu
- Metabolic Diseases
Gerasimos Sykiotis
Massachusetts General Hospital & Harvard Medical School, Clinical & Research Fellow in Reproductive Endocrinology
I have broad interests in the genetics of endocrine diseases, and especially in metabolism and reproduction. I am particularly interested in the role of cellular stress
response pathways in the homeostasis of the endocrine system
gsykiotis@partners.org
- Microbiology
Georgia Mitsi, PhD, MBA, MSc
United Biosource, Manager
Molecular Genetics, microbiology
yiolamitsi@yahoo.gr
- Nephrology
Pinelopi Kapitsinou
Vanderbilt University, Clinical Fellow
Contribution of hypoxia inducible factors (HIFs) in chronic kidney disease progression,and hypoxic regulation of erythropiesis
Pinelopi.kapitsinou@vanderbilt.edu
-Nervous system development
Nikolaos Giagtzoglou
Baylor College of Medicine, Post-doctoral fellow
Developmental Biology
giagtzog@bcm.tmc.edu
- Neurodegeneration
Evangelia Sotiriou
Columbia University, MD, Post-doctoral researcher
Mitochondrial Diseases
es2802@columbia.edu
Sotiria Sotiriou
UCSF-JHU-NIH, PhD candidate
Neurodegeneration, Post-transcriptional regulation
ria_sotiriou@hotmail.com
- Neuroscience
Dimitrios Arkilo, MD
Tufts, Floating Hospital for Children, Fellow, Pediatric Neurology
Hypothermia in neuroprotection. Neuronal migration defects
arkdimi@hotmail.com
Nikolaos Patsopoulos MD, PhD
Brigham & Women's Hospital, Harvard Medical School, Research Fellow
Statistical Genetics
npatsopoulos@rics.bwh.harvard.edu
- Pulmonary DIseases
Eleni Vergadi
Children's Hospital Boston, Research Fellow in Pediatrics
Pulmonary Diseases, Molecular Genetics , Immunology
eleni.vergadi@childrens.harvard.ed
- Other
Marianna Feretzaki
Duke University, Graduate student
Genetics of Cryptococcus neoformasn
mf55@duke.edu
Hellenic Bioscientific Association in the USA
HBA-USA
HBA-USA
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