HBA-USA members that conduct research on "Developmental Biology"
- Bone development
Charisios D. Tsiairis
Harvard University, Graduate student
I am working on the mechanism that regulates long bone growth. The main focus is on how Ihh signaling
determines the final length of a bone through the control of chondrocyte's activity.
tsiairis@fas.harvard.edu
Konstantinos Zarbalis
UC Davis, Dept. of Pathology/Shriners Hospitals, Assistant Professor
My research is focused on the development of the forebrain and craniofacial structures. Using the mouse as a model organism we analyze mechanisms and the molecular
control involved in developing the forebrain and face.
kzarbalis@ucdavis.edu
- Cancer
Ourania Andrisani
Purdue University, Professor
Signal transduction mechanisms mediating liver and prostate cancer; signal transduction mechanisms involved in neural crest cell differentiation
andrisao@purdue.edu
Kyriakos D. Economides
Sanofi-Aventis, Senior Research Investigator
I am primarily interested in generating mouse models for hematological malignancies
kyriakos.economides@sanofi-aventis.com
- Cardiac development
Chrissa Kioussi
Oregon State University, Assistant Professor
Transcriptional regulation of cardiac and muscle development and related diseases
chrissa.kioussi@oregonstate.edu
Maria Irene Kontaridis
Harvard/Beth Israel Deaconess Medical Center, Assistant Professor of Medicine
Understanding the signaling pathways that mediate cardiac developmental processes may reveal important clues into the cellular and molecular pathogenesis of heart
disease. Specifically, we want to understand how protein-tyrosine phosphatases (PTPs) relate to cardiac development and disease. Our lab's research efforts focus on
developmental biology, in vivo analysis of in mouse systems, including disease models, and cardiac biology and stem cell research using primary cultures. Currently,
we are studying mouse models in which we can assess the molecular pathogenesis of the cardiac defects associated with Noonan (NS) and LEOPARD (LS)
Syndromes, pediatric disorders both attributed primarily to mutations in Shp2, the SH2 domain-containing protein tyrosine phosphatase
mkontari@bidmc.harvard.edu
- Endocrinology
Gerasimos Sykiotis
Massachusetts General Hospital & Harvard Medical School, Clinical & Research Fellow in Reproductive Endocrinology
I have broad interests in the genetics of endocrine diseases, and especially in metabolism and reproduction. I am particularly interested in the role of cellular stress
response pathways in the homeostasis of the endocrine system
gsykiotis@partners.org
- Functional Genetics
Demetrios Kalaitzidis
Boston University, PhD
Characterization of dysregulated Rel/NF-kapppaB transcription factors in lymphoma development
dkalaitz@bu.edu
- Growth Factor & cytokine signaling
John M. Kyriakis
Tufts-New England Medical Center, Professor of Medicine
The Kyriakis laboratory studies the mechanisms by which growth, inflammatory and stress stimuli alter cell function. We are interested in how
polypeptide mitogens and proinflammatory cytokines trigger activation of protein kinases and, in turn, how these protein kinases influence gene
expression. We are also interested in dissecting the biological functions of specific protein kinase and gene regulatory pathways. Our work is
focused especially on the mitogen-activated protein kinases (MAPKs). We believe that elucidating these pathways, and their biological functions
will enable the identification of novel drug targets and the development of improved treatments for diseases such as atherosclerosis, cancer,
arthritis and the complications of diabetes.
JKyriakis@tufts-nemc.org
- Hearing disorders
Argyro J. Bizaki
Harvard Medical School, Department of Otolaryngology M.E.E.I
Molecular Biology in Otosclerosis-Hearing Disorders
argyro_bizaki@meei.harvard.edu
- Muscle Development
Christina Economos
Tufts University, Assistant Professor
christina.economos@tufts.edu
Chrissa Kioussi
Oregon State University, Assistant Professor
Transcriptional regulation of cardiac and muscle development and related diseases
chrissa.kioussi@oregonstate.edu
- Neuronal Development
Ourania Andrisani
Purdue University, Professor
Signal transduction mechanisms mediating liver and prostate cancer; signal transduction mechanisms involved in neural crest cell differentiation
andrisao@purdue.edu
Nikolaos Giagtzoglou
Baylor College of Medicine, Post-doctoral fellow
Developmental Biology
giagtzog@bcm.tmc.edu
Vassiliki Machairaki
Johns Hopkins School of Medicine, Post-doctoral fellow
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS AND INDUCED PLURIPOTENT STEM CELLS(iPS CELLS) TO NEURAL PRECURSORS.
USE OF BIOMIMETIC NANOFIBROUS SCAFFOLDS AS A SUBSTRATE FOR HESC-DERIVED NEURAL PRECURSORS.
HUMAN NEURAL STEM CELL-BIOMATRIX PREPARATIONS AS TOOLS IN RECONSTRUCTING NEURAL PATHWAYS
vmachai1@jhmi.edu
- Notch signaling
Spyros Artavanis-Tsakonas
Harvard Medical School, K. J. Isselbacher-P. Schwartz, Professor of Cell Biology
Molecular Genetics, Developmental Biology, Cell Signalling
tsakonas@helix.mgh.harvard.edu
- Bone development
Charisios D. Tsiairis
Harvard University, Graduate student
I am working on the mechanism that regulates long bone growth. The main focus is on how Ihh signaling
determines the final length of a bone through the control of chondrocyte's activity.
tsiairis@fas.harvard.edu
Konstantinos Zarbalis
UC Davis, Dept. of Pathology/Shriners Hospitals, Assistant Professor
My research is focused on the development of the forebrain and craniofacial structures. Using the mouse as a model organism we analyze mechanisms and the molecular
control involved in developing the forebrain and face.
kzarbalis@ucdavis.edu
- Cancer
Ourania Andrisani
Purdue University, Professor
Signal transduction mechanisms mediating liver and prostate cancer; signal transduction mechanisms involved in neural crest cell differentiation
andrisao@purdue.edu
Kyriakos D. Economides
Sanofi-Aventis, Senior Research Investigator
I am primarily interested in generating mouse models for hematological malignancies
kyriakos.economides@sanofi-aventis.com
- Cardiac development
Chrissa Kioussi
Oregon State University, Assistant Professor
Transcriptional regulation of cardiac and muscle development and related diseases
chrissa.kioussi@oregonstate.edu
Maria Irene Kontaridis
Harvard/Beth Israel Deaconess Medical Center, Assistant Professor of Medicine
Understanding the signaling pathways that mediate cardiac developmental processes may reveal important clues into the cellular and molecular pathogenesis of heart
disease. Specifically, we want to understand how protein-tyrosine phosphatases (PTPs) relate to cardiac development and disease. Our lab's research efforts focus on
developmental biology, in vivo analysis of in mouse systems, including disease models, and cardiac biology and stem cell research using primary cultures. Currently,
we are studying mouse models in which we can assess the molecular pathogenesis of the cardiac defects associated with Noonan (NS) and LEOPARD (LS)
Syndromes, pediatric disorders both attributed primarily to mutations in Shp2, the SH2 domain-containing protein tyrosine phosphatase
mkontari@bidmc.harvard.edu
- Endocrinology
Gerasimos Sykiotis
Massachusetts General Hospital & Harvard Medical School, Clinical & Research Fellow in Reproductive Endocrinology
I have broad interests in the genetics of endocrine diseases, and especially in metabolism and reproduction. I am particularly interested in the role of cellular stress
response pathways in the homeostasis of the endocrine system
gsykiotis@partners.org
- Functional Genetics
Demetrios Kalaitzidis
Boston University, PhD
Characterization of dysregulated Rel/NF-kapppaB transcription factors in lymphoma development
dkalaitz@bu.edu
- Growth Factor & cytokine signaling
John M. Kyriakis
Tufts-New England Medical Center, Professor of Medicine
The Kyriakis laboratory studies the mechanisms by which growth, inflammatory and stress stimuli alter cell function. We are interested in how
polypeptide mitogens and proinflammatory cytokines trigger activation of protein kinases and, in turn, how these protein kinases influence gene
expression. We are also interested in dissecting the biological functions of specific protein kinase and gene regulatory pathways. Our work is
focused especially on the mitogen-activated protein kinases (MAPKs). We believe that elucidating these pathways, and their biological functions
will enable the identification of novel drug targets and the development of improved treatments for diseases such as atherosclerosis, cancer,
arthritis and the complications of diabetes.
JKyriakis@tufts-nemc.org
- Hearing disorders
Argyro J. Bizaki
Harvard Medical School, Department of Otolaryngology M.E.E.I
Molecular Biology in Otosclerosis-Hearing Disorders
argyro_bizaki@meei.harvard.edu
- Muscle Development
Christina Economos
Tufts University, Assistant Professor
christina.economos@tufts.edu
Chrissa Kioussi
Oregon State University, Assistant Professor
Transcriptional regulation of cardiac and muscle development and related diseases
chrissa.kioussi@oregonstate.edu
- Neuronal Development
Ourania Andrisani
Purdue University, Professor
Signal transduction mechanisms mediating liver and prostate cancer; signal transduction mechanisms involved in neural crest cell differentiation
andrisao@purdue.edu
Nikolaos Giagtzoglou
Baylor College of Medicine, Post-doctoral fellow
Developmental Biology
giagtzog@bcm.tmc.edu
Vassiliki Machairaki
Johns Hopkins School of Medicine, Post-doctoral fellow
DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS AND INDUCED PLURIPOTENT STEM CELLS(iPS CELLS) TO NEURAL PRECURSORS.
USE OF BIOMIMETIC NANOFIBROUS SCAFFOLDS AS A SUBSTRATE FOR HESC-DERIVED NEURAL PRECURSORS.
HUMAN NEURAL STEM CELL-BIOMATRIX PREPARATIONS AS TOOLS IN RECONSTRUCTING NEURAL PATHWAYS
vmachai1@jhmi.edu
- Notch signaling
Spyros Artavanis-Tsakonas
Harvard Medical School, K. J. Isselbacher-P. Schwartz, Professor of Cell Biology
Molecular Genetics, Developmental Biology, Cell Signalling
tsakonas@helix.mgh.harvard.edu
Hellenic Bioscientific Association in the USA
HBA-USA
HBA-USA
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