HBA-USA members that conduct research on "Biological Chemistry"
- Cancer
Nektarios Barabutis, MSc, PhD
Miami MIller School of Medicine, University of Miami, Postdoctoral fellow
Modifications of erythrocyte membrane proteins in patients with hereditary spaerocytosis.
Oxidative alterations of erythrocyte proteins in diabetic patients
The role of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in cell physiology and metabolism.
The role and Signaling of Growth Hormone Releasing Hormone (GHRH) in cancer.
Effect of GHRH in ROS/RNS metabolism.
The role of Luteinizing Hormone Releasing Hormone (LHRH) in cancer and benign prostatic hyperplasia.
The role of GHRH agonistic and antagonistic analogs in human metabolism and disease.
nbarabutis@gmail.com
Evripidis Gavathiotis
Dana-Farber Cancer Institute/Children's Hospital Boston, Harvard Medical School, Instructor
We study the structure and function of apoptotic protein interactions that regulate life and death decisions in the cell. We aim to develop novel pharmacological
strategies and compounds to prevent protein interactions that cause cancer and cardiovascular disease and translate them into therapies.
We employ a multidisciplinary approach spanning chemistry, structural biology, biochemistry, cell biology and in vivo studies.
evripidis_gavathiotis@dfci.harvard.edu
Efstratios Katsoulidis, Ph.D.
Northwestern University, Research Assistant Professor
Biological Chemistry, Cancer, Hematology, Immunology
-katsoulidis@northwestern.edu
Anastasia Kalea
Feinberg School of Medicine-Northwestern University, Postdoctoral Research Fellow
Diabetes complications; Trace minerals; Functional Foods; Vascular structure and function; Cancer, Public Health
a-kalea@northwestern.edu
Sotirios Kampranis
Tufts University School of Medicine, Instructor
Structure, Epigenetic Regulation of Gene Expression and Cancer, Metabolic Engineering
s.kampranis@gmail.com
- Cardiovascular Disease
Konstantinos E. Hatzistergos
University of Miami, Post-doctoral fellow
Cardiovascular Disease, Immunology, Biological Chemistry, Animal Science
xatzistergos@hotmail.com
Maria Irene Kontaridis
Harvard/Beth Israel Deaconess Medical Center, Assistant Professor of Medicine
Understanding the signaling pathways that mediate cardiac developmental processes may reveal important clues into the cellular and molecular pathogenesis of heart
disease. Specifically, we want to understand how protein-tyrosine phosphatases (PTPs) relate to cardiac development and disease. Our lab's research efforts focus on
developmental biology, in vivo analysis of in mouse systems, including disease models, and cardiac biology and stem cell research using primary cultures. Currently,
we are studying mouse models in which we can assess the molecular pathogenesis of the cardiac defects associated with Noonan (NS) and LEOPARD (LS) Syndromes,
pediatric disorders both attributed primarily to mutations in Shp2, the SH2 domain-containing protein tyrosine phosphatase
mkontari@bidmc.harvard.edu
- Computational Biophysics/Biochemistry
Pavlos Maragakis
D. E. Shaw Research, Research Scientist
Computational Biophysics; Computational Biochemistry, Trying to understand the microscopic mechanisms of floppy, sticky, fluctuating, ever-changing proteins
- Evolution
Dimitra Chalkia
University of California, Irvine, Post-doctoral scholar
Role of naturally occurring human mitochondrial DNA variation in human health and disease; theoretical studies on the evolution of mitochondrial genes
dchalkia@uci.edu
Nikolas Nikolaidis
California State University, Fullerton, Assistant Professor
nnikolaidis@fullerton.edu
- Gene expression
Alexandros Petropoulos
Johns Hopkins Medical Institutions, Postdoctoral Research Scientist
Mechanism of action of ribosome-targeted antibiotics and Translation
apetrop1@jhmi.edu
- Medicinal Chemistry
Nikolaos Papaioannou
Wyeth Pharmaceuticals, Senior Research Scientist II, Medicinal Chemistry
Nikolaos.Papaioannou@hotmail.com
Malvina Papanastasiou
Northeastern University, Post-doctoral fellow
Use of tandem mass spectrometry to sequence ligand-protein covalent complexes. Our main goal is the mapping of the binding pockets of the two cannabinoid
receptors. Another major reserach area is the quantitation of the endocannabinoid metabolome by LC/MS/MS. The focus is to determine which components of the
endocannabinoid metabolome are affected by different drug, diet or disease states
m.papanastasiou@neu.edu
- Membrane trafficking
Stefanos Vassilopoulos
University of California, San Francisco, Post-doctoral fellow
I am currently working on CHC22, a clathrin isoform which is highly expressed in skeletal muscle. Studies to date indicate that CHC22 differs in function from the well
characterized clathrin (CHC17) that is involved in the ubiquitous membrane traffic pathways of receptor mediated endocytosis. My goal is to understand the role of this
unusual clathrin.
stephane.vassilopoulos@ucsf.edu
- Metabolic Diseases
Nektarios Barabutis, MSc, PhD
Miami MIller School of Medicine, University of Miami, Postdoctoral fellow
Modifications of erythrocyte membrane proteins in patients with hereditary spaerocytosis.
Oxidative alterations of erythrocyte proteins in diabetic patients
The role of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in cell physiology and metabolism.
The role and Signaling of Growth Hormone Releasing Hormone (GHRH) in cancer.
Effect of GHRH in ROS/RNS metabolism.
The role of Luteinizing Hormone Releasing Hormone (LHRH) in cancer and benign prostatic hyperplasia.
The role of GHRH agonistic and antagonistic analogs in human metabolism and disease.
nbarabutis@gmail.com
Gerasimos Sykiotis
Massachusetts General Hospital & Harvard Medical School, Clinical & Research Fellow in Reproductive Endocrinology
I have broad interests in the genetics of endocrine diseases, and especially in metabolism and reproduction. I am particularly interested in the role of cellular stress
response pathways in the homeostasis of the endocrine system
gsykiotis@partners.org
- Muscle research
Ioannis Grammatikakis
Baylor College of Medicine, PhD candidate
Muscle research, eukaryotic mRNA processing
grammati@bcm.edu
- Oxidative stress
Nektarios Barabutis, MSc, PhD
Miami MIller School of Medicine, University of Miami, Postdoctoral fellow
Modifications of erythrocyte membrane proteins in patients with hereditary spaerocytosis.
Oxidative alterations of erythrocyte proteins in diabetic patients
The role of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in cell physiology and metabolism.
The role and Signaling of Growth Hormone Releasing Hormone (GHRH) in cancer.
Effect of GHRH in ROS/RNS metabolism.
The role of Luteinizing Hormone Releasing Hormone (LHRH) in cancer and benign prostatic hyperplasia.
The role of GHRH agonistic and antagonistic analogs in human metabolism and disease.
nbarabutis@gmail.com
Harry Ischiropoulos
University of Pennsylvania, Associate Professor
ischirop@mail.med.upenn.edu
- Other
Sappho Gilbert
MIT, Student
Biological Chemistry, Cardiovascular Disease, Immunology, Clinical Pathology, Gene therapy
szg@mit.edu
- Cancer
Nektarios Barabutis, MSc, PhD
Miami MIller School of Medicine, University of Miami, Postdoctoral fellow
Modifications of erythrocyte membrane proteins in patients with hereditary spaerocytosis.
Oxidative alterations of erythrocyte proteins in diabetic patients
The role of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in cell physiology and metabolism.
The role and Signaling of Growth Hormone Releasing Hormone (GHRH) in cancer.
Effect of GHRH in ROS/RNS metabolism.
The role of Luteinizing Hormone Releasing Hormone (LHRH) in cancer and benign prostatic hyperplasia.
The role of GHRH agonistic and antagonistic analogs in human metabolism and disease.
nbarabutis@gmail.com
Evripidis Gavathiotis
Dana-Farber Cancer Institute/Children's Hospital Boston, Harvard Medical School, Instructor
We study the structure and function of apoptotic protein interactions that regulate life and death decisions in the cell. We aim to develop novel pharmacological
strategies and compounds to prevent protein interactions that cause cancer and cardiovascular disease and translate them into therapies.
We employ a multidisciplinary approach spanning chemistry, structural biology, biochemistry, cell biology and in vivo studies.
evripidis_gavathiotis@dfci.harvard.edu
Efstratios Katsoulidis, Ph.D.
Northwestern University, Research Assistant Professor
Biological Chemistry, Cancer, Hematology, Immunology
-katsoulidis@northwestern.edu
Anastasia Kalea
Feinberg School of Medicine-Northwestern University, Postdoctoral Research Fellow
Diabetes complications; Trace minerals; Functional Foods; Vascular structure and function; Cancer, Public Health
a-kalea@northwestern.edu
Sotirios Kampranis
Tufts University School of Medicine, Instructor
Structure, Epigenetic Regulation of Gene Expression and Cancer, Metabolic Engineering
s.kampranis@gmail.com
- Cardiovascular Disease
Konstantinos E. Hatzistergos
University of Miami, Post-doctoral fellow
Cardiovascular Disease, Immunology, Biological Chemistry, Animal Science
xatzistergos@hotmail.com
Maria Irene Kontaridis
Harvard/Beth Israel Deaconess Medical Center, Assistant Professor of Medicine
Understanding the signaling pathways that mediate cardiac developmental processes may reveal important clues into the cellular and molecular pathogenesis of heart
disease. Specifically, we want to understand how protein-tyrosine phosphatases (PTPs) relate to cardiac development and disease. Our lab's research efforts focus on
developmental biology, in vivo analysis of in mouse systems, including disease models, and cardiac biology and stem cell research using primary cultures. Currently,
we are studying mouse models in which we can assess the molecular pathogenesis of the cardiac defects associated with Noonan (NS) and LEOPARD (LS) Syndromes,
pediatric disorders both attributed primarily to mutations in Shp2, the SH2 domain-containing protein tyrosine phosphatase
mkontari@bidmc.harvard.edu
- Computational Biophysics/Biochemistry
Pavlos Maragakis
D. E. Shaw Research, Research Scientist
Computational Biophysics; Computational Biochemistry, Trying to understand the microscopic mechanisms of floppy, sticky, fluctuating, ever-changing proteins
- Evolution
Dimitra Chalkia
University of California, Irvine, Post-doctoral scholar
Role of naturally occurring human mitochondrial DNA variation in human health and disease; theoretical studies on the evolution of mitochondrial genes
dchalkia@uci.edu
Nikolas Nikolaidis
California State University, Fullerton, Assistant Professor
nnikolaidis@fullerton.edu
- Gene expression
Alexandros Petropoulos
Johns Hopkins Medical Institutions, Postdoctoral Research Scientist
Mechanism of action of ribosome-targeted antibiotics and Translation
apetrop1@jhmi.edu
- Medicinal Chemistry
Nikolaos Papaioannou
Wyeth Pharmaceuticals, Senior Research Scientist II, Medicinal Chemistry
Nikolaos.Papaioannou@hotmail.com
Malvina Papanastasiou
Northeastern University, Post-doctoral fellow
Use of tandem mass spectrometry to sequence ligand-protein covalent complexes. Our main goal is the mapping of the binding pockets of the two cannabinoid
receptors. Another major reserach area is the quantitation of the endocannabinoid metabolome by LC/MS/MS. The focus is to determine which components of the
endocannabinoid metabolome are affected by different drug, diet or disease states
m.papanastasiou@neu.edu
- Membrane trafficking
Stefanos Vassilopoulos
University of California, San Francisco, Post-doctoral fellow
I am currently working on CHC22, a clathrin isoform which is highly expressed in skeletal muscle. Studies to date indicate that CHC22 differs in function from the well
characterized clathrin (CHC17) that is involved in the ubiquitous membrane traffic pathways of receptor mediated endocytosis. My goal is to understand the role of this
unusual clathrin.
stephane.vassilopoulos@ucsf.edu
- Metabolic Diseases
Nektarios Barabutis, MSc, PhD
Miami MIller School of Medicine, University of Miami, Postdoctoral fellow
Modifications of erythrocyte membrane proteins in patients with hereditary spaerocytosis.
Oxidative alterations of erythrocyte proteins in diabetic patients
The role of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in cell physiology and metabolism.
The role and Signaling of Growth Hormone Releasing Hormone (GHRH) in cancer.
Effect of GHRH in ROS/RNS metabolism.
The role of Luteinizing Hormone Releasing Hormone (LHRH) in cancer and benign prostatic hyperplasia.
The role of GHRH agonistic and antagonistic analogs in human metabolism and disease.
nbarabutis@gmail.com
Gerasimos Sykiotis
Massachusetts General Hospital & Harvard Medical School, Clinical & Research Fellow in Reproductive Endocrinology
I have broad interests in the genetics of endocrine diseases, and especially in metabolism and reproduction. I am particularly interested in the role of cellular stress
response pathways in the homeostasis of the endocrine system
gsykiotis@partners.org
- Muscle research
Ioannis Grammatikakis
Baylor College of Medicine, PhD candidate
Muscle research, eukaryotic mRNA processing
grammati@bcm.edu
- Oxidative stress
Nektarios Barabutis, MSc, PhD
Miami MIller School of Medicine, University of Miami, Postdoctoral fellow
Modifications of erythrocyte membrane proteins in patients with hereditary spaerocytosis.
Oxidative alterations of erythrocyte proteins in diabetic patients
The role of Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in cell physiology and metabolism.
The role and Signaling of Growth Hormone Releasing Hormone (GHRH) in cancer.
Effect of GHRH in ROS/RNS metabolism.
The role of Luteinizing Hormone Releasing Hormone (LHRH) in cancer and benign prostatic hyperplasia.
The role of GHRH agonistic and antagonistic analogs in human metabolism and disease.
nbarabutis@gmail.com
Harry Ischiropoulos
University of Pennsylvania, Associate Professor
ischirop@mail.med.upenn.edu
- Other
Sappho Gilbert
MIT, Student
Biological Chemistry, Cardiovascular Disease, Immunology, Clinical Pathology, Gene therapy
szg@mit.edu
Hellenic Bioscientific Association in the USA
HBA-USA
HBA-USA
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